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The PA X protein, arising from ribosomal frameshift during PA translation, was recently discovered in influenza A virus (IAV). The C terminal domain X TM of PA X proteins in IAVs can be classified as full length (61 aa) or truncated (41 aa). In the main, avian influenza viruses express full length PA X proteins, whilst 2009 pandemic H1N1 (pH1N1) influenza viruses harbour truncated PA proteins.

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